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3-[4-(Aminomethyl)benzyloxy] Thalidomide SF-1-088

Product Name 3-[4-(Aminomethyl)benzyloxy] Thalidomide SF-1-088
Product Code A00009292
Chemical name 3-[4-(Aminomethyl)benzyloxy] Thalidomide SF-1-088
Synonyms
Impurity
CAS Number
Alternate CAS #
Molecular form C₅₃H₅₅N₅O₁₀S
Appearance
Melting Point
Mol. Weight 954.1
Storage
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Applications 3-[4-(Aminomethyl)benzyloxy] Thalidomide SF-1-088 is a potential small molecule inhibitor of Stat3 and Stat5-SH2 domain. Useful in the treatment of human cancers. Antileukemia agent. Derivative of Thalidomide (T338850), Inhibits FGF-induced angiogenesis. Inhibits replication of human immunodeficiency virus type 1. Teratogenic sedative. There is now a growing clinical interest in Thalidomide, and it is introduced as an immunomodulatory agent used primarily in combination with dexamethasone to treat multiple myeloma.
Dangerous Goods Info
References D’Amato, r.J., et al.: Proc. Natl. Acad. Sci. USA, 91, 4082 (1994), Makonkawkeyoon, S., et al.: Proc. Natl. Acad. Sci. USA, 90, 5974 (1993), Schumacher, H., et al.: J. Pharmacol. Exp. Therap., 160, 189 (1968)
Extra Notes
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3-[4-(Aminomethyl)benzyloxy] Thalidomide SF-1-088
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