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Abiraterone Isopropyl Ether-d7

Product Name Abiraterone Isopropyl Ether-d7
Product Code A0000121
Chemical name Abiraterone Isopropyl Ether-d7
Synonyms 3-((3S,8R,9S,10R,13S,14S)-3-Isopropoxy-d7-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)pyridine
Impurity
CAS Number NA
Alternate CAS # Unlabelled CAS# N/A
Molecular form C₂₇H₃₀D₇NO
Appearance
Melting Point
Mol. Weight 398.63
Storage
Solubility
Stability
Category Chiral Reagents, Impurities, Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals, Steroids
Boiling Point
Applications Abiraterone Isopropyl Ether-d7 is the labeled analog of Abiraterone Isoproply Ether (A108532), an impurity of Abiraterone (A108490), a steroidal cytochrome P 450 17α-hydroxylase-17,20-lyase inhibitor (CYP17), is currently undergoing phase II clinical trials as a potential drug for the treatment of androgen-dependent prostate cancer.
Dangerous Goods Info NA
References Denis, L., et al.: Cancer, 72, 3888 (1993); Potter, G.A., et al.: J. Med. Chem., 38, 2463 (1995); Denmeade, S., et al.: Nat. Rev., 2, 389 (2002); Scher, H., et al.: J. Clin. Oncol., 23, 8253 (2005)
Extra Notes
Documents (MSDS) No Data Available
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Abiraterone Isopropyl Ether-d7
Product Packings
2.5mg
25mg
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