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Abiraterone Isopropyl Ether

Product Name Abiraterone Isopropyl Ether
Product Code A0000120
Chemical name Abiraterone Isopropyl Ether
Synonyms 3-((3S,8R,9S,10R,13S,14S)-3-Isopropoxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)pyridine
Impurity
CAS Number NA
Alternate CAS # NA
Molecular form C₂₇H₃₇NO
Appearance White Solid
Melting Point 75-78°C
Mol. Weight 391.59
Storage -20°C Freezer
Solubility Chloroform (Slightly), Methanol (Slightly)
Stability
Category Chiral Reagents, Impurities, Pharmaceuticals, Intermediates & Fine Chemicals, Steroids
Boiling Point
Applications Abiraterone Isopropyl Ether is an impurity of Abiraterone (A108490), a steroidal cytochrome P 450 17α-hydroxylase-17,20-lyase inhibitor (CYP17), is currently undergoing phase II clinical trials as a potential drug for the treatment of androgen-dependent prostate cancer.
Dangerous Goods Info NA
References Denis, L., et al.: Cancer, 72, 3888 (1993); Potter, G.A., et al.: J. Med. Chem., 38, 2463 (1995); Denmeade, S., et al.: Nat. Rev., 2, 389 (2002); Scher, H., et al.: J. Clin. Oncol., 23, 8253 (2005)
Extra Notes
Documents (MSDS) No Data Available
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Abiraterone Isopropyl Ether
Product Packings
10mg
100mg
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