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Abiraterone N-Oxide

Product Name Abiraterone N-Oxide
Product Code A0000123
Chemical name Abiraterone N-Oxide
Synonyms
Impurity
CAS Number NA
Alternate CAS # NA
Molecular form C₂₄H₃₁NO₂
Appearance White Solid
Melting Point >240°C (dec.)
Mol. Weight 365.51
Storage Hygroscopic, Refrigerator, under inert atmosphere
Solubility Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
Stability
Category
Boiling Point
Applications Abiraterone N-Oxide is a derivative of Abiraterone (A108490), a steroidal cytochrome P 450 17α-hydroxylase-17,20-lyase inhibitor (CYP17), is currently undergoing phase II clinical trials as a potential drug for the treatment of androgen-dependent prostate cancer.
Dangerous Goods Info NA
References Denis, L., et al.: Cancer, 72, 3888 (1993), Potter, G.A., et al.: J. Med. Chem., 38, 2463 (1995), Denmeade, S., et al.: Nat. Rev., 2, 389 (2002), Scher, H., et al.: J. Clin. Oncol., 23, 8253 (2005),
Extra Notes
Documents (MSDS) No Data Available
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Abiraterone N-Oxide
Product Packings
2.5mg
5mg
10mg
25mg
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