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N-(3-(Aminomethyl)benzyl)acetamidine Dihydrochloride

Product Name N-(3-(Aminomethyl)benzyl)acetamidine Dihydrochloride
Product Code N00009330
Chemical name N-(3-(Aminomethyl)benzyl)acetamidine Dihydrochloride
Synonyms N-[[3-(Aminomethyl)phenyl]methyl]ethanimidamide Dihydrochloride; 1400W
Impurity
CAS Number 214358-33-5
Alternate CAS # Free Base: 180001-34-7
Molecular form C₁₀H₁₇Cl₂N₃
Appearance White to Off-White Solid
Melting Point 213-220°C
Mol. Weight 250.17
Storage -20°C Freezer
Solubility DMSO, Methanol, Water
Stability
Category Amines, Aromatics, Inhibitors, Nitric Oxide Reagents
Boiling Point
Applications N-(3-(Aminomethyl)benzyl)acetamidine Dihydrochloride is a selective inducible nitric oxide synthase (iNOS) inhibitor (1, 2, 3). A long-acting human iNOS inhibitor possessing an IC50 value of 2.0uM (1).
Dangerous Goods Info
References (1) Garvey, E.P., et al.: J. Biol. Chem. (1997) 272: 4959-63 (2) Thomsen, L.L., et al.: Cancer Res. (1997) 57: 3300-4 (3) Archer, E. J., et al.: ACS Synth. Biol. (2012) 1: 451–457
Extra Notes
Documents (MSDS) No Data Available
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N-(3-(Aminomethyl)benzyl)acetamidine Dihydrochloride
Product Packings
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