| Product Name | Abiaterone-5,6-epoxide |
| Product Code | A0000122 |
| Chemical name | Abiaterone-5,6-epoxide |
| Synonyms | 5,6-Epoxy Abiaterone |
| Impurity | |
| CAS Number | NA |
| Alternate CAS # | NA |
| Molecular form | C₂₄H₃₃NO₂ |
| Appearance | |
| Melting Point | |
| Mol. Weight | 367.52 |
| Storage | |
| Solubility | |
| Stability | |
| Category | |
| Boiling Point | |
| Applications | Abiaterone-5,6-Epoxide is an impurity of Abiraterone (A108490), which is a steroidal cytochrome P 450 17α-hydroxylase-17,20-lyase inhibitor (CYP17), is currently undergoing phase II clinical trials as a potential drug for the treatment of androgen-dependent prostate cancer. |
| Dangerous Goods Info | NA |
| References | Denis, L., et al.: Cancer, 72, 3888 (1993); Potter, G.A., et al.: J. Med. Chem., 38, 2463 (1995); Denmeade, S., et al.: Nat. Rev., 2, 389(2002); Scher, H., et al.: J. Clin. Oncol., 23, 8253 (2005) |
| Extra Notes | |
| Documents (MSDS) | No Data Available |
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