| Product Name | ABT-199-D10 |
| Product Code | A0000162 |
| Chemical name | ABT-199-D10 |
| Synonyms | Venetoclax-d10 |
| Impurity | |
| CAS Number | NA |
| Alternate CAS # | Unlabelled: 1257044-40-8 |
| Molecular form | C₄₅H₄₀D₁₀ClN₇O₇S |
| Appearance | |
| Melting Point | |
| Mol. Weight | 878.5 |
| Storage | |
| Solubility | |
| Stability | |
| Category | |
| Boiling Point | |
| Applications | ABT-199-D10 is a deuterized form of ABT 199 (A112430), which is a potent and selective BCL-2 inhibitor that achieves potent antitumor activity while sparing platelets. It’s practical application is to treat chronic lymphocytic leukaemic cells and estrogen receptor-positive breast cancer. |
| Dangerous Goods Info | NA |
| References | Davids, M. & Letai, A.: Cancer Cell, 23, 139 (2013); Souers, A.,et al.: Nat. Med., 19, 202 (2013); Vaillant, F., et al.: Cancer Cell, 24, 120 (2013); Vogler, M., et al.: Brit. J. Haematol., 163, 139 (2013); |
| Extra Notes | |
| Documents (MSDS) | No Data Available |
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