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Adaptaquin
| Product Name | Adaptaquin |
| Product Code | A00002913 |
| Chemical name | Adaptaquin |
| Synonyms | 7-[(4-Chlorophenyl)[(3-hydroxy-2-pyridinyl)amino]methyl]-8-quinolinol |
| Impurity | |
| CAS Number | 385786-48-1 |
| Alternate CAS # | NA |
| Molecular form | C₂₁H₁₆ClN₃O₂ |
| Appearance | |
| Melting Point | |
| Mol. Weight | 377.82 |
| Storage | |
| Solubility | |
| Stability | |
| Category | |
| Boiling Point | |
| Applications | General Uses: Ischemic injury Research, Renal anemia, HIF Prolyl Hydroxylase Inhibitor, Antioxidant, Neuroprotective Description: Adaptaquin inhibits the HIF PHDs in brain in a dose dependent fashion and penetrates blood brain barrier (BBB). Exhibited functional recovery in intra-cerebral hemorrhage rat model; inhibits ATF4 gene. Potent HIF PHD inhibitor (hypoxia inducible factor), Selective PDH2 inhibitor. This compound is suitable for pyruvate dehydrogenase (PDH) related research. |
| Dangerous Goods Info | NA |
| References | 1. Yang Y, et al. 2016. Transl Stroke Res. ; 7(6): 535–547. 2. Vaithinathan S, et al. 2016; Antioxid Redox Signal. 2014 Jun 1; 20(16): 2631–2665. |
| Extra Notes | |
| Documents (MSDS) | No Data Available |
| Keywords | Buy 385786-48-1 | Purchase 385786-48-1 | Order 385786-48-1 | 385786-48-1 supplier | 385786-48-1 manufacturer | 385786-48-1 distributor | 385786-48-1 cost |
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