| Product Name | Almorexant |
| Product Code | A00003966 |
| Chemical name | Almorexant |
| Synonyms | (αR,1S)-3,4-Dihydro-6,7-dimethoxy-N-methyl-α-phenyl-1-[2-[4-(trifluoromethyl)phenyl]ethyl]-2(1H)-isoquinolineacetamide; ACT 078573 |
| Impurity | |
| CAS Number | 871224-64-5 |
| Alternate CAS # | |
| Molecular form | C₂₉H₃₁F₃N₂O₃ |
| Appearance | |
| Melting Point | |
| Mol. Weight | 512.56 |
| Storage | |
| Solubility | |
| Stability | |
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| Boiling Point | |
| Applications | Almorexant is a dual orexin receptor antagonist ACT-541468 used in the treatment of insomnia. It regulates sleep and wakefulness through two G protein-coupled receptors, namely Orexin 1 receptor and Orexin 2 receptor. |
| Dangerous Goods Info | |
| References | Treiber, A., et al.: J. Pharmacol. Exp. Ther., 362, 489 (2017); Beuckmann, C. T., et al.: J. Pharmacol. Exp. Ther.,362, 287 (2017); Tang, L., et al.: Guoji Yaoxue Yanjiu Zazhi, 42, 85 (2015) |
| Extra Notes | |
| Documents (MSDS) | No Data Available |
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