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ent-Alvimopan
| Product Name | ent-Alvimopan |
| Product Code | E00004017 |
| Chemical name | ent-Alvimopan |
| Synonyms | 2-[[(2R)-2-Benzyl-3-[(3S,4S)-4-(3-Hydroxyphenyl)-3,4-dimethylpiperidin-1-yl]propanoyl]amino]acetic Acid; |
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| CAS Number | |
| Alternate CAS # | Isomer: 156053-89-3 |
| Molecular form | C₂₅H₃₂N₂O₄ |
| Appearance | |
| Melting Point | |
| Mol. Weight | 424.53 |
| Storage | |
| Solubility | |
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| Boiling Point | |
| Applications | ent-Alvimopan is the enantiomer of Alvimopan (A575800), which is a peripheral µ-opioid receptor antagonist and gastroprokinetic. Also, it is derived from (S)-4-Phenyl-2-oxazolidinone (P335820), which is an intermediate for the synthesis and development for cholesterol absorption inhibitor AZD4121. |
| Dangerous Goods Info | |
| References | Zimmerman, D.M., et al.: J. Med. Chem., 37, 2262 (1994), Liu, S.S., et al.: Clin. Pharmacol. Ther., 68, 66 (2000), Taguchi, A., et al.: N. Engl. J. Med., 345, 935 (2001); Soloshonok, V.A., et al.: Tetrahedron. Lett., 46, 1107 (2005); Luo, Y., et al.: Chinese. Chem. Lett., 17, 1551 (2006); Karlsson, S., et al.: Org. Process.Res. Develop., 16, 586 (2012); |
| Extra Notes | |
| Documents (MSDS) | No Data Available |
| Keywords | buy ent-Alvimopan | Purchase ent-Alvimopan | Order ent-Alvimopan | ent-Alvimopan supplier | ent-Alvimopan manufacturer | ent-Alvimopan distributor | ent-Alvimopan cost |
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