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(2R,3R,4R)-Alvimopan
| Product Name | (2R,3R,4R)-Alvimopan |
| Product Code | R00004051 |
| Chemical name | (2R,3R,4R)-Alvimopan |
| Synonyms | N-[(2R)-2-[[(3R,4R)-4-(3-Hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl]-1-oxo-3-phenylpropyl]glycine; 2-[[(2R)-2-Benzyl-3-[(3R,4R)-4-(3-Hydroxyphenyl)-3,4-dimethylpiperidin-1-yl]propanoyl]amino]acetic Acid; |
| Impurity | |
| CAS Number | 342639-35-4 |
| Alternate CAS # | Isomer: 156053-89-3 |
| Molecular form | C₂₅H₃₂N₂O₄ |
| Appearance | |
| Melting Point | |
| Mol. Weight | 424.53 |
| Storage | |
| Solubility | |
| Stability | |
| Category | |
| Boiling Point | |
| Applications | (2R,3R,4R)-Alvimopan is derived from (S)-4-Phenyl-2-oxazolidinone (P335820), which is an intermediate for the synthesis and development for cholesterol absorption inhibitor AZD4121. Also, it can be derived from ADL 08-0011 (A291800), which is a metabolite of Alvimopan (A575800). Alvimopan amide hydrolized metabolite. |
| Dangerous Goods Info | |
| References | Soloshonok, V.A., et al.: Tetrahedron. Lett., 46, 1107 (2005); Luo, Y., et al.: Chinese. Chem. Lett., 17, 1551 (2006); Karlsson, S., et al.: Org. Process.Res. Develop., 16, 586 (2012); Zimmerman, D., et al.: J. Med. Chem., 37, 2262 (1994), Kurz, A., et al.: Drugs, 63, 649 (2003), Neary, P., et al.: Expert. Opin Invest. Drugs, 4, 479 (2005) |
| Extra Notes | |
| Documents (MSDS) | No Data Available |
| Keywords | Buy 342639-35-4 | Purchase 342639-35-4 | Order 342639-35-4 | 342639-35-4 supplier | 342639-35-4 manufacturer | 342639-35-4 distributor | 342639-35-4 cost |
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