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4-(4-Amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamide
| Product Name | 4-(4-Amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamide |
| Product Code | A00004507 |
| Chemical name | 4-(4-Amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamide |
| Synonyms | 4-(4-Amino-3-fluorophenoxy)-N-methyl-2-pyridinecarboxamide; 4-(4-Amino-3-fluorophenoxy)pyridine-2-carboxylic Acid Methylamide |
| Impurity | |
| CAS Number | 757251-39-1 |
| Alternate CAS # | |
| Molecular form | C₁₃H₁₂FN₃O₂ |
| Appearance | C₁₃H₁₂FN₃O₂ |
| Melting Point | 135-137°C (dec.) |
| Mol. Weight | 261.25 |
| Storage | Room Temperature, under inert atmosphere |
| Solubility | Chloroform, DMSO, Methanol |
| Stability | |
| Category | Amines, Aromatics, Pharmaceuticals, Intermediates & Fine Chemicals |
| Boiling Point | |
| Applications | 4-(4-Amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamide is a compound used as a reagent to synthesize Regorafenib (R143000), a multikinase inhibitor that is used to treat patients with advanced colorectal cancer. |
| Dangerous Goods Info | |
| References | Mross, K., et al.: Clin. Cancer Res., 18, 2658 (2012); Stiehl, J., et al. Process for Preparation of Regorafenib. PCT Int. Appl. 2011128261. Oct 20, 2011; Van Cutsem, E., et al.: J. Clin. Oncol., 30, 3502 (2012) |
| Extra Notes | |
| Documents (MSDS) | No Data Available |
| Keywords | Buy 757251-39-1 | Purchase 757251-39-1 | Order 757251-39-1 | 757251-39-1 supplier | 757251-39-1 manufacturer | 757251-39-1 distributor | 757251-39-1 cost |
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