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cis-(-)-4-Amino-3-(3,4-dimethoxyphenyl)-1-methylpiperidine
| Product Name | cis-(-)-4-Amino-3-(3,4-dimethoxyphenyl)-1-methylpiperidine |
| Product Code | C00005053 |
| Chemical name | cis-(-)-4-Amino-3-(3,4-dimethoxyphenyl)-1-methylpiperidine |
| Synonyms | |
| Impurity | |
| CAS Number | 26722-58-7 |
| Alternate CAS # | |
| Molecular form | C₁₄H₂₄Cl₂N₂O₂ |
| Appearance | White Solid |
| Melting Point | |
| Mol. Weight | 363.26 |
| Storage | |
| Solubility | Methanol, Water |
| Stability | |
| Category | |
| Boiling Point | |
| Applications | Cis-(-)-4-Amino-3-(3,4-dimethoxyphenyl)-1-methylpiperidine is an intermediate in the synthesis of Tolafentrine (T531000), which is a dual-selective phosphodiesterase 3/4 inhibitor used in chronic experimental pulmonary hypertension. |
| Dangerous Goods Info | |
| References | Huxtable, R., et al.: Pharmacol. Ther., 47, 371 (1990), Tanaka, K., et al.: Cancer Res., 55, 2927 (1995), Wagner, R., et al.: J. Pharmacol. Exp. Ther., 282, 1650 (1997), Cowan, K., et al.: Nat. Med., 6, 698 (2000), Shankavaram, U., et al.: J. Biol. Chem., 276, 19027 (2001), |
| Extra Notes | |
| Documents (MSDS) | No Data Available |
| Keywords | Buy 26722-58-7 | Purchase 26722-58-7 | Order 26722-58-7 | 26722-58-7 supplier | 26722-58-7 manufacturer | 26722-58-7 distributor | 26722-58-7 cost |
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