4-Amino-1-[3,5-bis-O-(4-chlorobenzoyl)-2-deoxy-α-D-erythro-pentofuranosyl]-1,3,5-triazin-2(1H)-one
| Product Name |
4-Amino-1-[3,5-bis-O-(4-chlorobenzoyl)-2-deoxy-α-D-erythro-pentofuranosyl]-1,3,5-triazin-2(1H)-one
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| Product Code |
A00006897
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| Chemical name |
4-Amino-1-[3,5-bis-O-(4-chlorobenzoyl)-2-deoxy-α-D-erythro-pentofuranosyl]-1,3,5-triazin-2(1H)-one
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| Synonyms |
α-Decitabine-3’,5’-bis(4-chlorobenzoate); Decitabine USP Related Compound C
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| Impurity |
Decitabine USP Related Compound C
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| CAS Number |
1140891-02-6
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| Alternate CAS # |
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| Molecular form |
C₂₂H₁₈Cl₂N₄O₆
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| Appearance |
White to Off-White Solid
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| Melting Point |
>200°C (dec.)
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| Mol. Weight |
505.31
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| Storage |
Hygroscopic, -20°C Freezer, Under Inert Atmosphere
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| Solubility |
DMSO (Slightly), Methanol (Slightly, Heated)
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| Stability |
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| Category |
Amines, Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
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| Boiling Point |
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| Applications |
4-Amino-1-[3,5-bis-O-(4-chlorobenzoyl)-2-deoxy-α-D-erythro-pentofuranosyl]-1,3,5-triazin-2(1H)-one (Decitabine USP Related Compound C) is a derivative of α-Decitabine (D226730) which is shown to inhibit DNA methylation resulting in an effective anticancer agent.
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| Dangerous Goods Info |
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| References |
Hajek, M. et al.: Biochem. Pharm., 75, 965 (2008); Rogstad, D. et al.: Chem. Res. Toxicol., 22, 1194 (2009);
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| Extra Notes |
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| Documents (MSDS) |
Download Document
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| Keywords |
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