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4-Amino-1-[3,5-bis-O-(4-chlorobenzoyl)-2-deoxy-β-D-erythro-pentofuranosyl]-1,3,5-triazin-2(1H)-one

Product Name 4-Amino-1-[3,5-bis-O-(4-chlorobenzoyl)-2-deoxy-β-D-erythro-pentofuranosyl]-1,3,5-triazin-2(1H)-one
Product Code A00006898
Chemical name 4-Amino-1-[3,5-bis-O-(4-chlorobenzoyl)-2-deoxy-β-D-erythro-pentofuranosyl]-1,3,5-triazin-2(1H)-one
Synonyms β-Decitabine-3’,5’-bis(4-chlorobenzoate); Decitabine USP Related Compound B
Impurity Decitabine USP Related Compound B
CAS Number 1034301-08-0
Alternate CAS #
Molecular form C₂₂H₁₈Cl₂N₄O₆
Appearance White Solid
Melting Point >182°C (dec.)
Mol. Weight 505.31
Storage Hygroscopic, -20°C Freezer, Under Inert Atmosphere
Solubility Chloroform (Very Slightly, Heated), DMSO (Slightly), Methanol (Slightly, Heated)
Stability
Category Amines, Aromatics, Heterocycles, Nucleotides, Bases & Related Reagents, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point
Applications 4-Amino-1-[3,5-bis-O-(4-chlorobenzoyl)-2-deoxy-β-D-erythro-pentofuranosyl]-1,3,5-triazin-2(1H)-one (Decitabine USP Related Compound B) is a derivative of β-Decitabine (A796950) which is used as cancer treatment, in particular to inhibit the growth of pancreatic endocrine tumor cell lines.
Dangerous Goods Info
References Deng, T., et al.: Life Sci., 84, 311 (2009), Horne, H., et al.: Mol. Cancer Res., 7, 199 (2009), Zinner, R., et al.: Mol. Cancer Ther., 8, 521 (2009)
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4-Amino-1-[3,5-bis-O-(4-chlorobenzoyl)-2-deoxy-β-D-erythro-pentofuranosyl]-1,3,5-triazin-2(1H)-one
Product Packings
25mg
250mg
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