2-Amino-5-chlorobenzenesulfonamide
| Product Name |
2-Amino-5-chlorobenzenesulfonamide
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| Product Code |
A00007329
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| Chemical name |
2-Amino-5-chlorobenzenesulfonamide
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| Synonyms |
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| Impurity |
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| CAS Number |
5790-69-2
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| Alternate CAS # |
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| Molecular form |
C₆H₇ClN₂O₂S
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| Appearance |
Light Brown to Beige Solid
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| Melting Point |
144-150°C
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| Mol. Weight |
206.65
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| Storage |
-20°C Freezer
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| Solubility |
DMSO (Slightly), Methanol (Slightly)
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| Stability |
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| Category |
Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds
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| Boiling Point |
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| Applications |
2-Amino-5-chlorobenzenesulfonamide is a metabolite of IDRA-21 (I232500), which inhibits AMPA receptor desensitization and enhances cognition by a related mechanism. IDRA-21 is more able to cross the blood-brain barrier than Cyclothiazide (C988960).
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| Dangerous Goods Info |
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| References |
Cannazza, G., et. al.: Bioorg. Med. Chem. Lett., 19, 1254 (2009); Zivkovic, et al.: J. Pharmacol. Exp. Ther., 272, 300 (1995); Dingledine, R., et al.: Pharmacol. Rev., 51, 7 (1999); Sun, Y., et al.: Nature, 417, 245 (2002); Thomsen, R., et al.: J. Med. Chem., 49, 3315 (2006)
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| Extra Notes |
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| Documents (MSDS) |
No Data Available
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| Keywords |
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