5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside
| Product Name |
5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside
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| Product Code |
A00008592
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| Chemical name |
5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside
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| Synonyms |
5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside; AICAR; Acadesine; 5-Amino-1-β-D-ribofuranosyl-1H-imidazole-4-carboxamide; 5-Amino-4-imidazolecarboxamide Riboside; Arasine; GP 1-110; NSC 105823;
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| Impurity |
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| CAS Number |
2627-69-2
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| Alternate CAS # |
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| Molecular form |
C₉H₁₄N₄O₅
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| Appearance |
Off-White to Pale Beige Solid
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| Melting Point |
205-207°C (dec.)
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| Mol. Weight |
258.23
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| Storage |
-20°C Freezer
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| Solubility |
DMSO (Slightly), Methanol (Slightly), Water (Slightly)
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| Stability |
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| Category |
Carbohydrates & Derivatives, Nucleotides, Bases & Related Reagents,
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| Boiling Point |
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| Applications |
AICAR is a nucleoside analogue that is able to enter nucleoside pools and is able to significantly increase levels of adenosine during periods of ATP breakdown. Adenosine-regulating agents (ARAs) have been recognized for therapeutic potential in myocardial ischemia. Cardioprotective.
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| Dangerous Goods Info |
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| References |
Mullane, K., et al.: Trends Cardiovasc Med., 3, 227 (1993), Browne, G.J., et al.: J. Biol. Chem., 279, 13, 12220 (2004)
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| Extra Notes |
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| Documents (MSDS) |
Download Document
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| Keywords |
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