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1-[2-Amino-1-(4-methoxyphenyl)ethyl]cyclohexanol

Product Name 1-[2-Amino-1-(4-methoxyphenyl)ethyl]cyclohexanol
Product Code A00008674
Chemical name 1-[2-Amino-1-(4-methoxyphenyl)ethyl]cyclohexanol
Synonyms 1-[2-Amino-1-(p-methoxyphenyl)ethyl]cyclohexanol; Dinorvenlafaxine; D,L-N,N-Didesmethylvenlafaxine; Venlafaxine EP Impurity C
Impurity Venlafaxine EP Impurity C
CAS Number 93413-77-5
Alternate CAS # HCl: 130198-05-9
Molecular form C₁₅H₂₃NO₂
Appearance Yellow to Light Brown Oil
Melting Point N/A
Mol. Weight 249.35
Storage Refrigerator
Solubility Chloroform, Ethyl Acetate, Methanol
Stability
Category Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point
Applications 1-[2-Amino-1-(4-methoxyphenyl)ethyl]cyclohexanol is an intermediate in the synthesis of N,O-Didesmethylvenlafaxine, a metabolite of Venlafaxine (V120000), a selective serotonin noradrenaline reuptake inhibitor which may be used as an antidepressant (1,2).
Dangerous Goods Info
References 1. Klamerus. K. et al.: J. Clin. Pharmacol. 1992 Aug;32(8):716-24. 2. Gelenberg, J. et al.: JAMA. 2000;283(23):3082-3088
Extra Notes
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1-[2-Amino-1-(4-methoxyphenyl)ethyl]cyclohexanol
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