| Product Name | N-Acetyl-L-(-)-leucine |
| Product Code | N0000872 |
| Chemical name | N-Acetyl-L-(-)-leucine |
| Synonyms | (S)-2-Acetamido-4-methylpentanoic Acid; Acetyl-L-leucine; Acetylleucine; N-Acetyl-L-leucine; N-Acetylleucine; NSC 206316 |
| Impurity | |
| CAS Number | 1188-21-2 |
| Alternate CAS # | NA |
| Molecular form | C₈H₁₅NO₃ |
| Appearance | White Solid |
| Melting Point | 174-175°C |
| Mol. Weight | 173.21 |
| Storage | Refrigerator |
| Solubility | DMSO (Slightly), Ethanol (Slightly), Water (Slightly, Heated) |
| Stability | |
| Category | Miscellaneous Reagents, |
| Boiling Point | |
| Applications | N-Acetyl-L-(-)-leucine is used in the preparation of small molecule inhibitors of anti-apoptotic Bcl-2 family proteins. Also used in the preparation of amphiphilic copolymers involving hydrophobic amino acid and oligopeptide side chains for optical tumor imaging in vivo. |
| Dangerous Goods Info | NA |
| References | Zheng, C. et al.: Bioorg. Med. Chem. Lett., 22, 39 (2012); Miki, K. et al.: Bull. Chem. Soc. Jap., 85, 1277 (2012); |
| Extra Notes | |
| Documents (MSDS) | No Data Available |
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