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4-[(1E)-2-(2-Amino-4-hydroxy-5-methylphenyl)diazenyl]-N-2-pyridinylbenzenesulfonamide
| Product Name | 4-[(1E)-2-(2-Amino-4-hydroxy-5-methylphenyl)diazenyl]-N-2-pyridinylbenzenesulfonamide |
| Product Code | E00008721 |
| Chemical name | 4-[(1E)-2-(2-Amino-4-hydroxy-5-methylphenyl)diazenyl]-N-2-pyridinylbenzenesulfonamide |
| Synonyms | MS 436; |
| Impurity | |
| CAS Number | 1395084-25-9 |
| Alternate CAS # | |
| Molecular form | C₁₈H₁₇N₅O₃S |
| Appearance | |
| Melting Point | |
| Mol. Weight | 383.42 |
| Storage | |
| Solubility | |
| Stability | |
| Category | Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds, |
| Boiling Point | |
| Applications | MS 436 is a potent bromodomain inhibitor, binding to BRD4 and more tightly to subdomain BD1 than BD2. These domains play a key role in inflammatory gene expression, mitosis and viral/host interaction. Applications involving innhibition of bromodomains include decrease in cell proliferation for leukemia and destruction of tumor cells. |
| Dangerous Goods Info | |
| References | Gallenkamp, D. et al.: ChemMedChem, 9, 438 (2014); Zhang, G. et al.: J. med. Chem., 56, 9251 (2013); |
| Extra Notes | |
| Documents (MSDS) | No Data Available |
| Keywords | Buy 1395084-25-9 | Purchase 1395084-25-9 | Order 1395084-25-9 | 1395084-25-9 supplier | 1395084-25-9 manufacturer | 1395084-25-9 distributor | 1395084-25-9 cost |
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