5-Amino-2-methylbenzotrifluoride
| Product Name |
5-Amino-2-methylbenzotrifluoride
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| Product Code |
A00009731
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| Chemical name |
5-Amino-2-methylbenzotrifluoride
|
| Synonyms |
(4-Methyl-3-trifluoromethylphenyl)amine; 3-Trifluoromethyl-4-methylaniline; 4-Amino-2-trifluoromethyltoluene; 4-Methyl-3-(trifluoromethyl)aniline; 4-Methyl-3-(trifluoromethyl)benzenamine
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| Impurity |
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| CAS Number |
65934-74-9
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| Alternate CAS # |
|
| Molecular form |
C₈H₈F₃N
|
| Appearance |
Pale Orange to Light Brown Oil
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| Melting Point |
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| Mol. Weight |
175.15
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| Storage |
Refrigerator
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| Solubility |
DMSO (Slightly), Methanol (Slightly)
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| Stability |
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| Category |
Amines, Aromatics, Miscellaneous Reagents
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| Boiling Point |
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| Applications |
5-Amino-2-methylbenzotrifluoride is used to prepare azoles as inhibitors of VEGF receptors 1 and 2 with high intestinal permeability. It can also be used to prepare curcumin analogs conjugated with antiandrogens.
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| Dangerous Goods Info |
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| References |
Kiselyov, A., et al.: Bioorg. Med. Chem. Lett., 17, 1369 (2007); Shi, Q., et al.: Bioorg. Med. Chem., 20, 4020 (2012)
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| Extra Notes |
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| Documents (MSDS) |
No Data Available
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| Keywords |
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