(1S,4R)-4-(2-Amino-6-chloro-9H-purin-9-yl)-2-cyclopentene-1-carboxylate
| Product Name |
(1S,4R)-4-(2-Amino-6-chloro-9H-purin-9-yl)-2-cyclopentene-1-carboxylate
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| Product Code |
S00007360
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| Chemical name |
(1S,4R)-4-(2-Amino-6-chloro-9H-purin-9-yl)-2-cyclopentene-1-carboxylate
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| Synonyms |
(1S-cis)-4-(2-Amino-6-chloro-9H-purin-9-yl)-2-cyclopentene-1-carboxylate; Abacavir - In House Impurity; Abacavir Impurities; Abacavir Intermediates
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| Impurity |
Abacavir - In House Impurity
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| CAS Number |
1246819-78-2
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| Alternate CAS # |
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| Molecular form |
C₁₁H₁₀ClN₅O₂
|
| Appearance |
Pale Yellow Solid
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| Melting Point |
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| Mol. Weight |
279.68
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| Storage |
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| Solubility |
DMSO, Methanol
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| Stability |
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| Category |
Pharmaceuticals, Intermediates & Fine Chemicals, Nucleotides, Bases & Related Reagents
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| Boiling Point |
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| Applications |
(1S,4R)-4-(2-Amino-6-chloro-9H-purin-9-yl)-2-cyclopentene-1-carboxylate (Abacavir - In House Impurity) is intermediate of Abacavir Carboxylate (A105005), a major metabolite of Abacavir (A105000) in human urine and cerebrospinal fluid (1,2,3).
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| Dangerous Goods Info |
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| References |
(1) Jackson, A., et al.: Antivir Ther. 17, 19 (2012)
(2) Yuen, G. J., et al.: Clin Pharmacokinet. 47, 351 (2008)
(3) McDowell, J., et al.: Antimicrob. Agents Chemother., 43, 2855 (1999)
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| Extra Notes |
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| Documents (MSDS) |
No Data Available
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| Keywords |
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