(5R)-4-Acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-1,5-dihydro-3-hydroxy-2H-pyrrol-2-one
| Product Name |
(5R)-4-Acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-1,5-dihydro-3-hydroxy-2H-pyrrol-2-one
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| Product Code |
R00001938
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| Chemical name |
(5R)-4-Acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-1,5-dihydro-3-hydroxy-2H-pyrrol-2-one
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| Synonyms |
(R)-4-Acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-3-hydroxy-1,5-dihydro-2H-pyrrol-2-one;
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| Impurity |
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| CAS Number |
512177-83-2
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| Alternate CAS # |
NA
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| Molecular form |
C₁₈H₁₉ClFNO₃
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| Appearance |
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| Melting Point |
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| Mol. Weight |
351.8
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| Storage |
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| Solubility |
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| Stability |
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| Category |
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| Boiling Point |
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| Applications |
(5R)-4-Acetyl-1-(4-chloro-2-fluorophenyl)-5-cyclohexyl-1,5-dihydro-3-hydroxy-2H-pyrrol-2-one, is an allosteric antagonist of the C-C chemokine receptor type 2 (CCR2) with an IC50 of 103 nM.
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| Dangerous Goods Info |
NA
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| References |
Zweemer AJ, et al.: Mol Pharmacol. 2013 Oct;84(4):551-61.;
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| Extra Notes |
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| Documents (MSDS) |
No Data Available
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| Keywords |
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