(6α,9β,11β,16α)-21-(Acetyloxy)-9,11-epoxy-6-fluoro-17-hydroxy-16-methylpregna-1,4-diene-3,20-dione
| Product Name |
(6α,9β,11β,16α)-21-(Acetyloxy)-9,11-epoxy-6-fluoro-17-hydroxy-16-methylpregna-1,4-diene-3,20-dione
|
| Product Code |
A0000827
|
| Chemical name |
(6α,9β,11β,16α)-21-(Acetyloxy)-9,11-epoxy-6-fluoro-17-hydroxy-16-methylpregna-1,4-diene-3,20-dione
|
| Synonyms |
9,11β-Epoxy-6α-fluoro-17,21-dihydroxy-16α-methyl-9β-pregna-1,4-diene-3,20-dione 21-Acetate; 9,11-Epoxy-9H-cyclopenta[a]phenanthrene, Pregna-1,4-diene-3,20-dione deriv.
|
| Impurity |
|
| CAS Number |
4571-51-1
|
| Alternate CAS # |
NA
|
| Molecular form |
C₂₄H₂₉FO₆
|
| Appearance |
White Solid
|
| Melting Point |
|
| Mol. Weight |
432.48
|
| Storage |
|
| Solubility |
Chloroform
|
| Stability |
|
| Category |
Aromatics, Pharmaceuticals, Intermediates & Fine Chemicals, Steroids
|
| Boiling Point |
|
| Applications |
(6α,9β,11β,16α)-21-(Acetyloxy)-9,11-epoxy-6-fluoro-17-hydroxy-16-methylpregna-1,4-diene-3,20-dione is an intermediate in the synthesis of Paramethasone Acetate (P191845), a derivative of Dexamethasone (D298800), a potent synthetic member of the glucocorticoid class of steroid drugs that has anti-inflammatory and immunosuppressant properties.
|
| Dangerous Goods Info |
NA
|
| References |
Wershil, B.K., et al.: Int. Arch. Allergy Immunol., 107, 323 (1995), Riccardi, C., et al.: Cell Death Diff., 6, 1182 (1999), Llanos, S.L. and Roldan, A.: Bio Cell, 23, 29 (1999)
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| Extra Notes |
|
| Documents (MSDS) |
No Data Available
|
| Keywords |
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