| Product Name | (R,S,R)-2-Acetyl-4-(1,2,3,4-tetrahydroxybutyl)-imidazole-13C6 |
| Product Code | R00002289 |
| Chemical name | (R,S,R)-2-Acetyl-4-(1,2,3,4-tetrahydroxybutyl)-imidazole-13C6 |
| Synonyms | 1-[5-[(1R,2S,3R)-1,2,3,4-Tetrahydroxybutyl]-1H-imidazol-2-yl]-ethanone-13C6; [1R-(1R*,2S*,3R*)]-1-[4-(1,2,3,4-Tetrahydroxybutyl)-1H-imidazol-2-yl]-ethanone13C6 |
| Impurity | |
| CAS Number | 1448358-08-4 |
| Alternate CAS # | Unlabelled: 94944-70-4 |
| Molecular form | C₃¹³C₆H₁₄N₂O₅ |
| Appearance | Light Grey Solid |
| Melting Point | >221°C (dec.) |
| Mol. Weight | 236.17 |
| Storage | -20°C Freezer |
| Solubility | DMSO |
| Stability | |
| Category | Isotope Labelled Compounds, Amines, Aromatics, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals |
| Boiling Point | |
| Applications | (R,S,R)-2-Acetyl-4-(1,2,3,4-tetrahydroxybutyl)-imidazole-13C6 is the isotope labelled analog of (R,S,R)-2-Acetyl-4-(1,2,3,4-tetrahydroxybutyl)-imidazole (A188490). (R,S,R)-2-Acetyl-4-(1,2,3,4-tetrahydroxybutyl)-imidazole (THI) inhibits sphinogosine-1-phosphate (S1P) lyase for treatment of autoimmune disorders. |
| Dangerous Goods Info | NA |
| References | Zhang, H., et al.: Tetrahedron, 69, 4041 (2013); Bagdanoff, J.T., et al.: J. Med. Chem., 53, 8650 (2010); Bagdanoff, J.T., et al.: J. Med. Chem., 52, 3941 (2009) |
| Extra Notes | |
| Documents (MSDS) | No Data Available |
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