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1-Acetyl-4-(4-hydroxyphenyl)piperazine
| Product Name | 1-Acetyl-4-(4-hydroxyphenyl)piperazine |
| Product Code | A00001924 |
| Chemical name | 1-Acetyl-4-(4-hydroxyphenyl)piperazine |
| Synonyms | 1-[4-(4-Hydroxyphenyl)-1-piperazinyl]ethanone; 4-(4-Acetylpiperazino)phenol; 1-Acetyl-4-(p-hydroxyphenyl)piperazine; Ketoconazole Intermediate (branched chain of ketoconazole) |
| Impurity | |
| CAS Number | 67914-60-7 |
| Alternate CAS # | NA |
| Molecular form | C₁₂H₁₆N₂O₂ |
| Appearance | White to Off-White Solid |
| Melting Point | 180-182ºC |
| Mol. Weight | 220.27 |
| Storage | -20°C Freezer |
| Solubility | DMSO (Slightly), Methanol (Slightly) |
| Stability | |
| Category | Amines, Aromatics, Pharmaceuticals, Intermediates & Fine Chemicals |
| Boiling Point | |
| Applications | 1-Acetyl-4-(4-hydroxyphenyl)piperazine is an intermediate used to prepare Ketoconazole (K186000) which inhibits cytochrome P-450 dependent steps in the biosynthesis of steroid hormones in vivo. |
| Dangerous Goods Info | NA |
| References | Lambert, A., et al.: Biochem. Pharmacol., 35, 3999 (1986), Van Wauwe, J.P. and Janssen, P.A.J., J. Med. Chem., 32, 2231 (1989), Nardone, P.A., et al.: . Surg. Res., 44, 425 (1988), Tucker, W.F.G., et al.: Br. Med. J., 293, 882 (1986) |
| Extra Notes | |
| Documents (MSDS) | Download Document |
| Keywords | Buy 67914-60-7 | Purchase 67914-60-7 | Order 67914-60-7 | 67914-60-7 supplier | 67914-60-7 manufacturer | 67914-60-7 distributor | 67914-60-7 cost |
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