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2-Amino-5,6-dichloro-3,4-dihydroquinazoline
| Product Name | 2-Amino-5,6-dichloro-3,4-dihydroquinazoline |
| Product Code | A00004725 |
| Chemical name | 2-Amino-5,6-dichloro-3,4-dihydroquinazoline |
| Synonyms | 5,6-Dichloro-1,4-dihydro-2-quinazolinamine; RL 603; |
| Impurity | |
| CAS Number | 444904-63-6 |
| Alternate CAS # | |
| Molecular form | C₈H₇Cl₂N₃ |
| Appearance | C₈H₇Cl₂N₃ |
| Melting Point | 205-208ºC |
| Mol. Weight | 216.07 |
| Storage | Hygroscopic, -20°C Freezer, Under inert atmosphere |
| Solubility | DMSO (Slightly), Methanol (Slightly) |
| Stability | |
| Category | Amines, Aromatics, Heterocycles, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals |
| Boiling Point | |
| Applications | 2-Amino-5,6-dichloro-3,4-dihydroquinazoline is a metabolite of Anagrelide (A637300), a phosphodiesterase inhibitor with antiplatelet activity. Used as an antithrombocythemic. |
| Dangerous Goods Info | |
| References | Fleming, J.S., et al.: Thromb. Res., 15, 373 (1979); Seiler, S., et al.: J. Pharmacol. Exp. Ther., 243, 767 (1984); Silverstein, M. N., et al.: N. Engl. J. Med., 318, 1292 (1988); Spencer, C.M., et al.: Drugs, 47, 809 (1994) |
| Extra Notes | |
| Documents (MSDS) | No Data Available |
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