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2-Amino-5-chlorobenzenesulfonamide

Product Name 2-Amino-5-chlorobenzenesulfonamide
Product Code A00007329
Chemical name 2-Amino-5-chlorobenzenesulfonamide
Synonyms
Impurity
CAS Number 5790-69-2
Alternate CAS #
Molecular form C₆H₇ClN₂O₂S
Appearance Light Brown to Beige Solid
Melting Point 144-150°C
Mol. Weight 206.65
Storage -20°C Freezer
Solubility DMSO (Slightly), Methanol (Slightly)
Stability
Category Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds
Boiling Point
Applications 2-Amino-5-chlorobenzenesulfonamide is a metabolite of IDRA-21 (I232500), which inhibits AMPA receptor desensitization and enhances cognition by a related mechanism. IDRA-21 is more able to cross the blood-brain barrier than Cyclothiazide (C988960).
Dangerous Goods Info
References Cannazza, G., et. al.: Bioorg. Med. Chem. Lett., 19, 1254 (2009); Zivkovic, et al.: J. Pharmacol. Exp. Ther., 272, 300 (1995); Dingledine, R., et al.: Pharmacol. Rev., 51, 7 (1999); Sun, Y., et al.: Nature, 417, 245 (2002); Thomsen, R., et al.: J. Med. Chem., 49, 3315 (2006)
Extra Notes
Documents (MSDS) No Data Available
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2-Amino-5-chlorobenzenesulfonamide
Product Packings
500mg
2.5g
10g
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