5-Acetoxy-2-bromo-1,4-naphthoquinone
| Product Name |
5-Acetoxy-2-bromo-1,4-naphthoquinone
|
| Product Code |
A0000951
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| Chemical name |
5-Acetoxy-2-bromo-1,4-naphthoquinone
|
| Synonyms |
2-Bromo-5-acetoxy-1,4-naphthoquinone; 5-Acetoxy-2-bromo-1,4-naphthalenedione
|
| Impurity |
|
| CAS Number |
77189-69-6
|
| Alternate CAS # |
NA
|
| Molecular form |
C₁₂H₇BrO₄
|
| Appearance |
Yellow Solid
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| Melting Point |
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| Mol. Weight |
295.09
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| Storage |
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| Solubility |
Chloroform, Dichloromethane, Ethyl Acetate, Methanol
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| Stability |
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| Category |
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| Boiling Point |
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| Applications |
5-Acetoxy-2-bromo-1,4-naphthoquinone is an intermediate in the synthesis of Plumbagin-d3 (P627002). Plumbagin-d3 is labelled Plumbagin (P627000) which induces apoptosis in cancer cells. It also inhibits NADPH oxidase 4 in a time- and dose-dependent manner.
|
| Dangerous Goods Info |
NA
|
| References |
Klotz, L., et al.: Molecules, 19 14902 (2014); Gupta, S., et al.: Cancer Metastasis Rev., 29, 405 (2010); Schramm, A., et al.: Vascul. Pharmacol., 56, 216 (2012)
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| Extra Notes |
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| Documents (MSDS) |
No Data Available
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| Keywords |
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