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5-Amino-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazole-3-thiol
| Product Name | 5-Amino-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazole-3-thiol |
| Product Code | A00007068 |
| Chemical name | 5-Amino-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazole-3-thiol |
| Synonyms | 5-Amino-4-(4-cyclopropyl-1-naphthalenyl)-2,4-dihydro-3H-1,2,4-triazole-3-thione; 3-Amino-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazole-5-thiol; |
| Impurity | |
| CAS Number | 878671-96-6 |
| Alternate CAS # | |
| Molecular form | C₁₅H₁₄N₄S |
| Appearance | |
| Melting Point | |
| Mol. Weight | 282.36 |
| Storage | |
| Solubility | |
| Stability | |
| Category | |
| Boiling Point | |
| Applications | 5-Amino-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazole-3-thiol is a derivative of 5-Amino-4-(4-cyclopropyl-1-naphthalenyl)-2,4-dihydro-3H-1,2,4-Triazol-3-one (A602165), which is an impurity of the drug Lesinuard (L329700), which is used to synthesize febuxostat, a non-purine analog inhibitor of xanthine oxidase. Febuxostat is approved by the European Medicines Agency and the US Food and Drug Administration for treating gout. |
| Dangerous Goods Info | |
| References | Burns, C., et al.: Lancet 377, 165 (2011); Miner, J. et al.: PCT Int. Appl. WO 2011159732 A1 20111222 (2011); Crittenden, D. B. et al.: Clinical Investigation 1, 1563-1575 (2011) |
| Extra Notes | |
| Documents (MSDS) | No Data Available |
| Keywords | Buy 878671-96-6 | Purchase 878671-96-6 | Order 878671-96-6 | 878671-96-6 supplier | 878671-96-6 manufacturer | 878671-96-6 distributor | 878671-96-6 cost |
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