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5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside

Product Name 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside
Product Code A00008592
Chemical name 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside
Synonyms 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside; AICAR; Acadesine; 5-Amino-1-β-D-ribofuranosyl-1H-imidazole-4-carboxamide; 5-Amino-4-imidazole carboxamide Riboside; Arasine; GP 1-110; NSC 105823;
Impurity
CAS Number 2627-69-2
Alternate CAS #
Molecular form C₉H₁₄N₄O₅
Appearance Off-White to Pale Beige Solid
Melting Point 205-207°C (dec.)
Mol. Weight 258.23
Storage -20°C Freezer
Solubility DMSO (Slightly), Methanol (Slightly), Water (Slightly)
Stability
Category Carbohydrates & Derivatives, Nucleotides, Bases & Related Reagents,
Boiling Point
Applications AICAR is a nucleoside analogue that is able to enter nucleoside pools and is able to significantly increase levels of adenosine during periods of ATP breakdown. Adenosine-regulating agents (ARAs) have been recognized for therapeutic potential in myocardial ischemia. Cardioprotective.
Dangerous Goods Info
References Mullane, K., et al.: Trends Cardiovasc Med., 3, 227 (1993), Browne, G.J., et al.: J. Biol. Chem., 279, 13, 12220 (2004)
Extra Notes
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5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside
Product Packings
50mg
100mg
1g
2g
5g
10g
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