| Product Name | A-385358 |
| Product Code | A000037 |
| Chemical name | A-385358 |
| Synonyms | 4-[[(R)-3-Dimethylamino-1-[(phenylsulfanyl)methyl]propyl]amino]-N-[4-(4,4-dimethylpiperidin-1-yl)benzoyl]-3-nitrobenzenesulfonamide |
| Impurity | |
| CAS Number | 406228-55-5 |
| Alternate CAS # | NA |
| Molecular form | C₃₂H₄₁N₅O₅S₂ |
| Appearance | |
| Melting Point | |
| Mol. Weight | 639.83 |
| Storage | |
| Solubility | |
| Stability | |
| Category | |
| Boiling Point | |
| Applications | A-385358, is a selective inhibitor of Bcl-XL with Kis, in vitro. In vivo, A-385358, in combination with the lower dose of paclitaxel produces a significant reduction in tumor growth (%T/C) compare with paclitaxel monotherapy. |
| Dangerous Goods Info | NA |
| References | Shoemaker, A. R. et al.: Cancer Res. 2006 Sep 1;66(17):8731-9; |
| Extra Notes | |
| Documents (MSDS) | No Data Available |
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