| Product Name | AMG-458 |
| Product Code | A00009400 |
| Chemical name | AMG-458 |
| Synonyms | 1-(2-Hydroxy-2-methylpropyl)-N-[5-[(7-methoxyquinolin-4-yl)oxy]pyridin-2-yl]-5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide; 2,3-Dihydro-1-(2-hydroxy-2-methylpropyl)-N-[5-[(7-methoxy-4-quinolinyl)oxy]-2-pyridinyl]-5-methyl-3-oxo-2-phenyl-1H-pyrazole-4-carboxamide; |
| Impurity | |
| CAS Number | 913376-83-7 |
| Alternate CAS # | |
| Molecular form | C₃₀H₂₉N₅O₅ |
| Appearance | |
| Melting Point | |
| Mol. Weight | 539.58 |
| Storage | |
| Solubility | |
| Stability | |
| Category | |
| Boiling Point | |
| Applications | AMG-458 is a potent inhibitor of c-Met with an IC50 of 60 nM. |
| Dangerous Goods Info | |
| References | Liu, Longbin., et al.: J. Med. Chem., 51, 3688 (2008); |
| Extra Notes | |
| Documents (MSDS) | No Data Available |
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