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Abemaciclib
| Product Name | Abemaciclib |
| Product Code | A0000187 |
| Chemical name | Abemaciclib |
| Synonyms | N-[5-[(4-Ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl]-2-pyrimidinamine; LY 2835219; N-(5-((4-ethylpiperazin-1-yl)methyl)pyridin-2-yl)-5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-amine |
| Impurity | |
| CAS Number | 1231929-97-7 |
| Alternate CAS # | NA |
| Molecular form | C₂₇H₃₂F₂N₈ |
| Appearance | Light Yellow Solid |
| Melting Point | 175-178°C |
| Mol. Weight | 506.59 |
| Storage | -20°C Freezer |
| Solubility | Chloroform (Slightly), Methanol (Slightly) |
| Stability | |
| Category | |
| Boiling Point | |
| Applications | Abemaciclib is a potent and selective inhibitor of cyclin-dependent kinases, CDK4 and CDK6, as a method to inhibit the proliferation of cancer cells. |
| Dangerous Goods Info | NA |
| References | O’Leary, Ben., et al.: Nat Rev Clin Oncol., 13, 417 (2016); Van Arsdale., et al.: Clin. Cancer Res., 21, 2905 (2015); |
| Extra Notes | |
| Documents (MSDS) | No Data Available |
| Keywords | Buy 1231929-97-7 | Purchase 1231929-97-7 | Order 1231929-97-7 | 1231929-97-7 supplier | 1231929-97-7 manufacturer | 1231929-97-7 distributor | 1231929-97-7 cost |
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