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Abiaterone-5,6-epoxide

Product Name Abiaterone-5,6-epoxide
Product Code A0000122
Chemical name Abiaterone-5,6-epoxide
Synonyms 5,6-Epoxy Abiaterone
Impurity
CAS Number NA
Alternate CAS # NA
Molecular form C₂₄H₃₃NO₂
Appearance
Melting Point
Mol. Weight 367.52
Storage
Solubility
Stability
Category
Boiling Point
Applications Abiaterone-5,6-Epoxide is an impurity of Abiraterone (A108490), which is a steroidal cytochrome P 450 17α-hydroxylase-17,20-lyase inhibitor (CYP17), is currently undergoing phase II clinical trials as a potential drug for the treatment of androgen-dependent prostate cancer.
Dangerous Goods Info NA
References Denis, L., et al.: Cancer, 72, 3888 (1993); Potter, G.A., et al.: J. Med. Chem., 38, 2463 (1995); Denmeade, S., et al.: Nat. Rev., 2, 389 (2002); Scher, H., et al.: J. Clin. Oncol., 23, 8253 (2005)
Extra Notes
Documents (MSDS) No Data Available
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Abiaterone-5,6-epoxide
Product Packings
1mg
2mg
5mg
10mg
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