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Acivicin
| Product Name | Acivicin |
| Product Code | A00002565 |
| Chemical name | Acivicin |
| Synonyms | (αS,5S)-α-Amino-3-chloro-4,5-dihydro-5-isoxazoleacetic Acid; [S-(R*,R*)]-α-Amino-3-chloro-4,5-dihydro-5-isoxazoleacetic Acid; AT 125; Antibiotic AT 125; NSC 163501; U 42126; (+)-Acivicin |
| Impurity | |
| CAS Number | 42228-92-2 |
| Alternate CAS # | NA |
| Molecular form | C₅H₇ClN₂O₃ |
| Appearance | White to Off-White Solid |
| Melting Point | >177°C (dec.) |
| Mol. Weight | 178.57 |
| Storage | Hygroscopic, Refrigerator, under inert atmosphere |
| Solubility | Dichloromethane (Slightly, Heated), Water (Slightly, Sonicated) |
| Stability | |
| Category | Amines, Chiral Reagents, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals |
| Boiling Point | |
| Applications | Azaserine and Acivicin are classical and irreversible inhibitors of γ-Glutamyltranspeptidase (GGT). Acivicin is a potent antitumor antibiotic that induces apoptosis in human lymphoblastoid cells. |
| Dangerous Goods Info | NA |
| References | Hanigan, M., et al.: Biochemistry, 32, 6302 (1993); Suzuki, H., et al.: J. Bacteriol., 175, 6038 (1993); Suzuki, H., et al.: J. Biol. Chem., 277, 43536 (2002); Magdalena, L., et al.: Biochem. Pharma., 77, 76 (2009) |
| Extra Notes | |
| Documents (MSDS) | Download Document |
| Keywords | Buy 42228-92-2 | Purchase 42228-92-2 | Order 42228-92-2 | 42228-92-2 supplier | 42228-92-2 manufacturer | 42228-92-2 distributor | 42228-92-2 cost |
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