| Product Name | AdipoRon |
| Product Code | A00003026 |
| Chemical name | AdipoRon |
| Synonyms | 2-(4-Benzoylphenoxy)-N-[1-(phenylmethyl)-4-piperidinyl]acetamide; 2-(4-Benzoylphenoxy)-N-(1-benzylpiperidin-4-yl)acetamide |
| Impurity | |
| CAS Number | 924416-43-3 |
| Alternate CAS # | NA |
| Molecular form | C₂₇H₂₈N₂O₃ |
| Appearance | White to Off-White Solid |
| Melting Point | 106-108°C |
| Mol. Weight | 428.52 |
| Storage | Refrigerator |
| Solubility | Chloroform (Slightly), Methanol (Slightly) |
| Stability | |
| Category | Agonist, Amines, Aromatics, Pharmaceuticals, Intermediates & Fine Chemicals |
| Boiling Point | |
| Applications | AdipoRon is an AdipoR agonist and activates AMPK and PPAR-α pathways in the muscle and liver. AdipoRon ameliorated diabetes of genetically obese rodent model db/db mice, and prolonged the shortened lifespan of db/db mice on a high-fat diet. AdipoRon is a promising therapeutic approach for the treatment of obesity-related diseases such as type 2 diabetes. |
| Dangerous Goods Info | NA |
| References | Okada-Iwabu, M., et. al.: Nature, 503, 493 (2013) |
| Extra Notes | |
| Documents (MSDS) | No Data Available |
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